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Bystander activation and anti-tumor effects of CD8+ T cells following Interleukin-2 based immunotherapy is independent o... PDF available through Get Fulltext Research

Monjazeb, Arta M Tietze, Julia K Grossenbacher, Steven K Hsiao, Hui-Hua Zamora, Anthony E Mirsoian, Annie Koehn, Brent Blazar, Bruce R Weiss, Jonathan M Wiltrout, Robert H ...

Published in PloS one

We have previously demonstrated that immunotherapy combining agonistic anti-CD40 and IL-2 (IT) results in synergistic anti-tumor effects. IT induces expansion of highly cytolytic, antigen-independent "bystander-activated" (CD8(+)CD44high) T cells displaying a CD25(-)NKG2D(+) phenotype in a cytokine dependent manner, which were responsible for the a...

Attenuated age-impact on systemic inflammatory markers in the presence of a metabolic burden. PDF available through Get Fulltext Research

Erdembileg, A Mirsoian, A Enkhmaa, B Zhang, W Beckett, La William Murphy Berglund, Lf

Published in PLoS ONE

Resveratrol Prevents High Fluence Red Light-Emitting Diode Reactive Oxygen Species-Mediated Photoinhibition of Human Ski... PDF available through Get Fulltext Research

A, Mamalis E, Koo Rr, Isseroff William Murphy J, Jagdeo

Published in PLoS ONE

Background: Skin fibrosis is a significant medical problem that leads to a functional, aesthetic, and psychosocial impact on quality-of-life. Light-emitting diode-generated 633-nm red light (LED-RL) is part of the visible light spectrum that is not known to cause DNA damage and is considered a safe, non-invasive, inexpensive, and portable potential...

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