CpG expedites regression of local and systemic tumors when combined with activatable nanodelivery.
...Published in Journal of Controlled Release
Ultrasonic activation of nanoparticles provides the opportunity to deliver a large fraction of the injected dose to insonified tumors and produce a complete local response. Here, we evaluate whether the local and systemic response to chemotherapy can be enhanced by combining such a therapy with locally-administered CpG as an immune adjuvant. In ord...