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Natural killer cell immunotherapy to target stem-like tumor cells

Grossenbacher, Steven K. Canter, Robert J. Murphy, William J.

Published in Journal for ImmunoTherapy of Cancer

Advances in cancer immunotherapy are leading to its increasing and successful application for the treatment of solid–tissue cancers. Despite the recent advances there are still significant barriers, in particular, evidence for significant tumor heterogeneity, both genetic and epigenetic that limit long-term efficacy. Subpopulations of “stem-like” t...

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