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Models to Study NK Cell Biology and Possible Clinical Application.

Zamora, Anthony E Grossenbacher, Steven K Aguilar, Ethan G Murphy, William J

Published in Current protocols in immunology

Natural killer (NK) cells are large granular lymphocytes of the innate immune system, responsible for direct targeting and killing of both virally infected and transformed cells. NK cells rapidly recognize and respond to abnormal cells in the absence of prior sensitization due to their wide array of germline-encoded inhibitory and activating recept...

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