Boeckh, Michael Murphy, William J Peggs, Karl S
Published in
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
The 2015 Tandem American Society for Blood and Marrow Transplantation/Center for International Blood and Marrow Transplant Meetings provide an opportunity to review the current status and future perspectives on therapy for cytomegalovirus (CMV) infection in the setting of hematopoietic stem cell transplantation (HSCT). After many years during which...
Boeckh, Michael Murphy, William J Peggs, Karl S
Published in
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
The 2015 Tandem American Society for Blood and Marrow Transplantation/Center for International Blood and Marrow Transplant Meetings provide an opportunity to review the current status and future perspectives on therapy for cytomegalovirus (CMV) infection in the setting of hematopoietic stem cell transplantation (HSCT). After many years during which...
Ames, Erik Harouna, Salif Meyer, Colin Welniak, Lisbeth A Murphy, William J
Published in
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
The synthetic triterpenoid CDDO-Me has been shown to directly inhibit the growth of myeloid leukemias and lends itself to a wide array of therapeutic indications, including inflammatory conditions, because of its inhibition of NF-κB. We have previously demonstrated protection from acute graft-versus-host disease after CDDO-Me administration in an a...
Boeckh, M William Murphy Peggs, Ks
Published in
Biology of Blood and Marrow Transplantation
The 2015 Tandem American Society for Blood and Marrow Transplantation/Center for International Blood and Marrow Transplant Meetings provide an opportunity to review the current status and future perspectives on therapy for cytomegalovirus (CMV) infection in the setting of hematopoietic stem cell transplantation (HSCT). After many years during which...
Pai, Chien-Chun Steven Hsiao, Hui-Hua Sun, Kai Chen, Mingyi Hagino, Takeshi Tellez, Joseph Mall, Christine Blazar, Bruce R Monjazeb, Arta Abedi, Mehrdad
...
Published in
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
Bortezomib, a proteasome inhibitor capable of direct antitumor effects, has been shown to prevent acute graft-versus-host disease (GVHD) when administered in a short course immediately after bone marrow transplantation (BMT) in mice. However, when bortezomib is given continuously, CD4(+) T cell-mediated gastrointestinal tract damage increases GVHD ...
William Murphy Artz, As Champlin, Re Koreth, J Longo, Dl Van Den Brink, Mr
Published in
Biology of Blood and Marrow Transplantation
A serious dichotomy currently exists in hematopoietic stem cell transplantation (HSCT) and cancer research. Cancer is a disease that predominantly affects older people, yet there is a paucity of cancer research addressing the very unique needs of this population. Even basic biologic processes that exist in aging (decline in immune competency, incre...
Murphy, William J Parham, Peter Miller, Jeffrey S
Published in
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
After decades of mouse and human research, we now know that natural killer (NK) cells have unique properties including memory. Although initially described as major histocompatibility complex (MHC) unrestricted killers, NK cells have several families of receptors that directly recognize MHC including Ly49 receptors in the mouse and killer immunoglo...
