The role of antigen-specific and non-specific immunotherapy in the treatment of cancer.

Published in Journal of immunotoxicology

Immunotherapy in the treatment of cancer is increasing, particularly with the recent FDA approval of sipuleucel-T and ipilimumab. The efficacy of anti-tumor immunotherapies has been modest compared to their theoretical and pre-clinical promise. This review evaluates the promise and pitfalls of immunotherapy and highlight some of the obstacles to im...

Sensitization of human breast cancer cells to natural killer cell-mediated cytotoxicity by proteasome inhibition

Published in Clinical & Experimental Immunology

Effects of cancer immunotherapy regimens on primary vs. secondary immune responses and the potential impact on long-term...

Published in Adv Exp Med Biol: Crossroads Between Innate and Adaptive Immunity II

Treating metastatic solid tumors with bortezomib and a tumor necrosis factor-related apoptosis-inducing ligand receptor ...

Published in J Natl Cancer Inst

Proteasome Inhibition: Potential for Sensitization of Immune Effector Mechanisms in Cancer

Neuroendocrine hormones such as growth hormone and prolactin are integral members of the immunological cytokine network

Published in Immunology and Cell Biology

Differential effects of donor T cell cytokines on outcome with continuous bortezomib administration following allogeneic...

Published in Blood

Raising the specta of T-cell profiling

Published in Blood

TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection

Published in Blood

CTL-Promoting Effects of CD40 Stimulation Outweigh B Cell-Stimulatory Effects Resulting in B Cell Elimination and Diseas...

Published in Journal of Japan Society of Immunology & Allergology in Otolaryngology